A PRIZE IN THIS FIELD COULD PROVIDE THE NEEDED INCENTIVE TO REVOLUTIONIZE THIS FIELD
We aim to launch a large-scale, high-profile, incentivized prize competition to stimulate investment in research and development worth far more than the prize itself. We aim do this together with the X PRIZE foundation – that for instance led the Super-Efficient Automobile X Prize, the Oil Cleanup X Prize and the Ansary Space Flight X Prize – all of which successfully reached their respective audacious, but achievable goals.
We envision a $10M prize for the first team to transplant a vital organ into five humans or human size mammals that lacks their own, with 3 months’ post-transplant survival, having stored each organ below –120oC for at least a week before transplantation.
WHY A HIGH-TAKES/HIGH-PROFILE PRIZES LEAD TO THE NEEDED BREAKTHROUGHS
Historically, High-stakes/high-publicity prizes attracted teams from fields that were surprising and surprising fusions disparate expertize from unexpected places. There are several examples of how these teams become winners.
It is likely that a prize would stimulate and provide an incentive to focus on this challenge for research companies like 21st Century Medicine, Arigos Biomedical, Medical Biostasis , the researchers that are conducting relevant research in Russia and the cryobiology expertise from other places in the world, for instance at the large (if not still largest in the world) cryobiology center in the Ukraine.
As, or perhaps more importantly, other interesting expertise that can lead to competitive teams that perhaps could crack the remaining organ cryo problems. Some more or less wild guesses could include:
- The suspended animation/reduced metabolism research performed by e.g. Dr Mark Roth at the Fred Hutchinson Cancer Research Center as well as at the company Ikari that currently has a suspended animation protocol in Phase 2 FDA clinical trials;
- The genomics work that is being done at MIT and other universities to better understand cell stress and how to construct therapeutics that can help harden cells against both stress and toxins;
- Carbon nanotechnology, high-throughout molecule discovery systems, the civilian and army research into deep hypothermic practices as well as stem cell and other regenerative medicine research could potentially also play roles in achieving best optimal cryo preservation and revival of organs